OUR FACILITY CORES

The cores provide an infrastructure capable of supporting Hypothesis Generation, Hypothesis Testing studies and those that Translate into practice the concepts generated by the Center’s researchers. These cores aim to foster integration, coordination, and interdisciplinary cooperation among investigators and trainees at various stages of professional development, conducting high-quality research related to the effects of environmental factors on human health.

  • Virtual Repository and Protocol Development
  • Metagenomics, Metatransciptiomics
  • Gnotobiotic mice
  • Metabolic Phenotyping
  • RNA/DNA Quality
  • microRNA Detection
  • DNA Size Selection with Pippen Prep
  • Real Time PCR
  • Sequencing Library Prep
  • Cellular Bioenergetics
  • Statistical Analyses
  • Integromics and Higher Level Computational Analyses
  • Transmission electron microscopy
  • Optical microscopy – digital imaging/analysis
  • Live cell imaging (a) – widefield, confocal, multiphoton, TIRF microscopy
  • Live cell imaging (b) – FRAP, FLIP, FRET, photoactivation/conversion, time lapse
  • High throughput, automated fluorescence microscopy and image analysis
  • Multiplexing and quantitative readout; image processing, analysis, quantification
  • Superresolution microscopy
  • Basic Pronuclear Injection
  • Pronuclear Injection of CRISPR/CAS9 and TALEN
  • Blastocyst Injection/Chimera Production
  • Sperm Cryopreservation
  • Embryo Cryopreservation
  • Rederivation via IVF
  • Embryo Transfer
  • Colony Expansion/Maintenance
  • Gene Targeting via Homologous Recombination (Constitutive or Conditional)
  • ES cell Electroporation and Screening
  • Knockout Mice from Repository
  • Gene Trapped ES cells from Repository