QUANTITATIVE BIOLOGY CORE

RNA/DNA Quality

microRNA Detection

DNA Size Selection with Pippen Prep

Real Time PCR

Sequencing Library Prep

Cellular Bioenergetics

Statistical Analyses

Integromics and Higher Level Computational Analyses

ADVANCED IMAGING CORE

Transmission electron microscopy

Optical microscopy – digital imaging/analysis

Live cell imaging (a) – widefield, confocal, multiphoton, TIRF microscopy

Live cell imaging (b) – FRAP, FLIP, FRET, photoactivation/conversion, time lapse

High throughput, automated fluorescence microscopy and image analysis

Multiplexing and quantitative readout; image processing, analysis, quantification

Superresolution microscopy

INTEGRATED HEALTH SCIENCES CORE

Virtual Repository and Protocol Development

Metagenomics, Metatransciptiomics

Gnotobiotic mice

Metabolic Phenotyping

TARGETED GENOMICS CORE

Basic Pronuclear Injection

Pronuclear Injection of CRISPR/CAS9 and TALEN

Blastocyst Injection/Chimera Production

Sperm Cryopreservation

Embryo Cryopreservation

Rederivation via IVF

Embryo Transfer

Colony Expansion/Maintenance

Gene Targeting via Homologous Recombination (Constitutive or Conditional)

ES cell Electroporation and Screening

Knockout Mice from Repository

Gene Trapped ES cells from Repository